منابع مشابه
Motifs from the deep
Because of the increasing recognition of the importance of non-coding RNAs in gene regulation, there is considerable interest in identifying RNA motifs in genomic data. In a recent report in BMC Genomics, Breaker and colleagues describe a new algorithm for identifying functional noncoding RNAs in metagenomic sequences of marine organisms, a strategy that may be particularly effective for discov...
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Motifs are repeating patterns that determine the local properties of networks. In this work, we characterized all 3-node motifs using enzyme commission numbers of the International Union of Biochemistry and Molecular Biology to show that motif abundance is related to biochemical function. Further, we present a comparative analysis of motif distributions in the metabolic networks of 21 species a...
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Mining frequently occurring temporal motion patterns (motion motifs) is important for understanding, organizing and retrieving motion data. However, without any a priori knowledge of the motifs, such as their lengths, contents, locations and total number, it remains a challenging problem due to the enormous computational cost involved in analyzing huge motion databases. Moreover, since the same...
متن کاملMutational signatures and mutable motifs in cancer genomes.
Cancer is a genetic disorder, meaning that a plethora of different mutations, whether somatic or germ line, underlie the etiology of the 'Emperor of Maladies'. Point mutations, chromosomal rearrangements and copy number changes, whether they have occurred spontaneously in predisposed individuals or have been induced by intrinsic or extrinsic (environmental) mutagens, lead to the activation of o...
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Inferring topological and geometrical information from data can offer an alternative perspective on machine learning problems. Methods from topological data analysis, e.g., persistent homology, enable us to obtain such information, typically in the form of summary representations of topological features. However, such topological signatures often come with an unusual structure (e.g., multisets ...
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ژورنال
عنوان ژورنال: ACM Transactions on Graphics
سال: 2019
ISSN: 0730-0301,1557-7368
DOI: 10.1145/3272127.3275038